Disease Risks and Precautions
in Central Africa
provided below is for informational purposes only.
It may not be current, and it should not be considered definitive.
should check the Center for Disease Control (CDC) website
for the most current disease risk and disease prevention information.
DISEASES TRANSMITTED BY INSECTS
DISEASES TRANSMITTED THROUGH
FOOD AND WATER
DISEASES TRANSMITTED THROUGH
SUMMARY OF RECOMMENDATIONS
FOR CENTRAL AFRICA
COUNTRIES IN REGION
Angola, Cameroon, Central African Republic, Chad, Congo, Equatorial
Guinea, Gabon, Sudan, Zaire, and Zambia
Travelers to Central Afica may be exposed to potential diseases
from a number of sources. The most frequently reported illness
is traveler's diarrhea, but there are other diseases which are
unique to Africa or the tropics. These diseases are transmitted
by insects, contaminated food and water, or close contact with
infected people. Specific diseases are discussed under each of
these topical headings.
In order to reduce the risk of infection travelers must (1) protect
themselves from insects, (2) ensure the quality of their food
and drinking water, and (3) be knowledgeable about potential diseases
in the region to be visited. Finally, diseases are not restricted
to cleanly defined geographical areas, i.e. mosquitoes can fly
over city or country borders, therefore, all travelers should
protect themselves by taking the basic preventive precautions.
DISEASES TRANSMITTED BY INSECTS
Many diseases are transmitted through the bite of infected insects
such as mosquitoes, flies, fleas, ticks, and lice. In general
travelers must protect themselves from insect bites by wearing
proper clothing, using bednets, applying an insect repellent to
exposed skin and clothing, and if possible, avoiding high risk
situations, i.e. outdoor activities during night time hours from
dusk to dawn when mosquitoes bite, unscreened living accommodations,
etc. If a mosquito net is unlikely to be available, consideration
should be given to purchasing a portable mosquito net.
Risk: In Angola, Cameroon, Central African Republic, Chad, Congo,
Equatorial Guinea, Gabon, Sudan, Zaire, and Zambia a HIGH RISK
for malaria exists throughout the year in all parts of these countries,
including the urban areas. Zimbabwe: All areas except no risk
in Harare. The dominant form is P. falciparum (the most dangerous
type), which has been reported to be resistant to the drug chloroquine.
Prevention: Travelers at risk for malaria should take MEFLOQUINE
to prevent malaria. This drug is marketed in the United States
under the name Lariam . The adult dosage is 250 mg (one tablet)
once a week. MEFLOQUINE should be taken one week before leaving,
weekly while in the malarious area, and weekly for 4 weeks after
leaving the malarious area.
In addition to using drugs to prevent malaria and treat a possible
malaria attack, travelers should use measures to reduce exposure
to malaria-carrying mosquitoes, and protect themselves from mosquito
bites. These mosquitoes bite mainly during the evening and night,
from dusk to dawn.
Risk: Outbreaks of yellow fever have occurred in Angola, Sudan,
and Zaire. Yellow fever is not always active in all countries
of this region, but there is a significant risk to alltravelers
throughout the year, especially in travel or visits to rural settings.
Prevention: NOTE: SOME COUNTRIES REQUIRE YELLOW FEVER VACCINATION
FOR ENTRY. (See "REQUIREMENTS" below.) In general, if
you are traveling to a Central African country, the easiest and
safest thing to do is to get a yellow fever vaccination and a
signed certificate. Yellow fever vaccination, a one dose shot,
may be administered to adults and children over 9 months of age.
This vaccine is only administered at designated yellow fever centers,
usually your local health department. If at continued risk a booster
is needed every 10 years. Infants under 4 months MUST NOT be immunized.
Also, persons severely allergic to eggs should not be given the
vaccine. Generally, persons able to eat eggs or egg products can
safely receive the vaccine. The vaccine is not recommended for
persons who are pregnant or whose immune systems are not functioning
normally. In addition to the vaccine travelers should use measures
to reduce exposure to mosquitoes and protect themselves from mosquito
bites. These mosquitoes bite mainly during the evening hours.
REQUIREMENTS: PLEASE NOTE: If you are traveling to most countries
in West Africa, CDC RECOMMENDS AND MANY COUNTRIES REQUIRE A YELLOW
FEVER VACCINATION. (Yellow fever vaccine is the ONLY vaccine that
may be officially required for entry into certain countries.)
Zambia has no Yellow Fever Vaccination requirements.
Chad recommends but does not require yellow fever vaccination.
A certificate may be required when leaving Sudan.
5 CENTRAL AFRICAN COUNTRIES ABSOLUTELY REQUIRE A YELLOW FEVER
Central African Republic
In addition if you are traveling TO / FROM a country listed below
you are required to have a yellow fever vaccination.
TRAVELING FROM "ENDEMIC" YELLOW FEVER INFECTED COUNTRIES
Sao Tome and Principe
TRAVELING TO CENTRAL AFRICAN COUNTRIES BELOW:
Yellow Fever Certificate:
After immunization an International Certificate of Vaccination
is issued and is valid 10 days after vaccination to meet entry
and exit requirements for all countries. The Certificate is good
for 10 years. You must take the certificate with you. Travelers
who have a medical reason not to receive the yellow fever vaccine
should obtain a medical waiver. Most countries will accept a medical
waiver for persons with a medical reason not to receive the vaccine
(e.g. infants less than 4 months old, pregnant women, persons
hypersensitive to eggs, or those with an immunosuppressed condition.)
Risk: Dengue fever occurs sporadically in Cameroon, Congo, Gabon,
and Zaire, with epidemics most recently in Angola and Sudan. The
risk of infection is small for most travelers except during periods
of epidemic transmission.
Prevention: There is no vaccine for dengue fever therefore the
traveler should avoid mosquito bites. These mosquitoes bite mainly
in the daytime.
OTHER INSECT DISEASES
Risks: Other diseases spread by mosquitoes, sand flies, black
flies, or other insects are prevalent, especially in rural areas.
These diseases include: Filariasis and Chikungunya (mosquito),
leishmaniasis (sandfly), Onchocerciasis (blackflies), Trypanosomiasis
(fleas), Congo-Crimean Hemorrhagic Fever (tick), typhus (lice),
and Plague (fleas).
PREVENTING INSECT BITES
To reduce mosquito bites travelers should remain in well-screened
areas, use mosquito nets, and wear clothes that cover most of
the body. Travelers should also take insect repellent with them
to use on any exposed areas of the skin. The most effective repellent
is DEET (N,N-diethyl meta-toluamide) an ingredient in most insect
repellents. Travelers should also purchase a flying insect-killing
spray to use in living and sleeping areas during the evening and
night. For greater protection clothing and bednets can be soaked
in or sprayed with PERMETHRIN, which is an insect repellent licensed
for use on clothing. If applied according to the directions, permethrin
will repel insects from clothing for several weeks.
DISEASES TRANSMITTED THROUGH FOOD AND
Food and waterborne diseases are the number one cause of illness
to travelers and are very common in the Indian Subcontinent. Traveler's
diarrhea is the most frequent health problem for travelers. It
can be caused by viruses, bacteria, or parasites which are found
universally throughout the region. Transmission is most often
through contaminated food or water. Infections cause diarrhea
and vomiting (typhoid fever, cholera, and parasites), liver damage
(hepatitis), or muscle paralysis (polio).
Risk: Travelers to the Central Africa are at risk for typhoid
fever, especially when traveling to smaller cities, villages,
or rural areas. Zaire recommends a typhoid vaccination.
Prevention: By drinking only bottled or boiled water and eating
only thoroughly cooked food, a traveler lowers the risk of infection.
Currently available vaccines have been shown to protect 70- 90%
of the recipients. Therefore, even vaccinated travelers should
be cautious in selecting their food and water. Two available vaccines
provide equivalent protection against typhoid fever -- oral and
Recommendations: CDC recommends a typhoid vaccination for those
travelers who are going off the usual tourist itineraries, traveling
to smaller cities and rural areas, or staying long term, that
is, a traveler for six weeks or more. Typhoid vaccination is not
required for international travel.
Risk: Cholera cases have been reported from most of the countries
of Central Africa. The risk of infection to the U. S. traveler
is low, especially those that are following the usual tourist
itineraries and staying in standard accommodations. Travelers
should consider the vaccine if they have stomach ulcers, use anti-acid
therapy, or if they will be living in less than sanitary conditions
in areas of high cholera activity.
Prevention: Travelers to cholera infected areas should follow
the standard food and water precautions of eating only thoroughly
cooked food, peeling their own fruit, and drinking either boiled
water, bottled carbonated water, or bottled carbonated soft drinks.
Persons with severe cases respond well to simple fluid and electrolyte-replacement
therapy, but medical attention must be sought quickly when cholera
is suspected. The available vaccine is only 50% effective in reducing
the illness, and is not recommended routinely for travelers.
Risk: Travelers are at high risk for Hepatitis A, especially if
travel plans include visiting rural areas and extensive travel
in the countryside, frequent close contact with local persons,
or eating in settings of poor sanitation. A study has shown that
many cases of travel-related hepatitis A occur in travelers to
developing countries with "standard" itineraries, accommodations,
and food consumption behaviors.
Prevention: The virus is inactivated by boiling or cooking to
85 degrees centigrade for one minute, therefore eating thoroughly
cooked foods and drinking only treated water serve as general
precautions. Havrix, the hepatitis A vaccine currently licensed
for use in the U.S., or immune globulin (IG) is recommended before
travel for persons 2 years of age or older. Hepatitis A vaccine
is preferred for persons who plan to travel repeatedly or reside
for long periods of time in intermediate or high risk areas. Immune
globulin is recommended for travelers < 2 years of age. Immune
globulin is recommended for persons of all ages who desire only
short term protection.
Recommendations: CDC recommends hepatitis A vaccine or IG for
protection against hepatitis A. For travelers over 18 years of
age, hepatitis A vaccine should be given in a two dose series
with the second dose administered 6-12 months after the first.
Immune globulin should be used for travelers < 2 years of age.
Immune globulin is recommended for persons of all ages who desire
only short term protection.
Risk: Travelers to Central Africa are at risk of parasitic infections.
There are many types of parasites and infection may occur in several
ways: by eating undercooked meats infected with parasites or their
larva; by eating food or drinking water contaminated with parasites
or their eggs; by contact with soil or water infected with parasites;
or through insect bites. Several types of parasites can penetrate
intact skin and travelers are advised to wear shoes.
Prevention: Travelers should eat only thoroughly cooked food,
drink safe water, wear shoes, refrain from swimming in fresh water,
and avoid contact with insects, particularly mosquitoes, biting
flies, gnats, and midges.
DISEASES TRANSMITTED THROUGH INTIMATE
AIDS / HIV
Risk: AIDS is found throughout the region. In Central Africa,
heterosexual transmission accounts for the majority of the cases,
with men and women more of less equal. In addition, many women
of child bearing age are infected, and HIV transmission from mother
to infant is widespread. The risk to a traveler depends on whether
the traveler will be involved in sexual or needle-sharing contact
with a person who is infected with HIV. Receipt of unscreened
blood for transfusion poses a risk for HIV infection.
Prevention: No effective vaccine has been developed for HIV. Travelers
should avoid sexual or needle-sharing contact with a person who
is infected with HIV. If a blood transfusion is necessary, screened
blood should be from an HIV-negative blood donor.
Recommendations: Travelers should avoid activities known to carry
risks for infection with HIV.
Risk: The risk of Hepatitis B virus infection is high for Central
Africa. The risk to the individual international traveler is determined
by the extent of: (1) direct contact with blood or other body
fluids, etc.; (2) intimate sexual contact with an infected person;
(3) the duration of travel.
Prevention: The primary prevention consists of either vaccination
and/or reducing intimate contact with those suspected of being
infected. For those travelers expecting to reside in countries
of high risk, as well as all health workers, vaccination is strongly
recommended. Vaccination should ideally begin 6 months before
travel, in order to complete the full series.
Recommendations: CDC recommends vaccination for any of the following
people: any health care worker (medical, dental, or laboratory)
whose activities might result in blood exposure; any traveler
who may have intimate sexual contact with the local population;
any long-term (6 months or more) traveler, e.g. teachers, who
will reside in rural areas or have daily physical contact with
the local population; or any traveler who is likely to seek either
medical, dental, or other treatment in local facilities during
their stay. Hepatitis B vaccination is not required for travel
to any country.
Risk: There is aseasonal risk of meningococcal disease in parts
of Central Africa primarily during the dry season from December
to June. When a traveler lives and works around the local population,
the risk increases.
Prevention: A one dose vaccine called Menomune is available.
Recommendations: Vaccination is not required for entry into any
country in this region. CDC recommends vaccination with meningococcal
vaccine for travelers going to Mali and all countries directly
eastward, including Cameroon, Central African Republic, Chad,
and Sudan, when travel occurs between December and June.
Risk: Schistosomiasis infection is widespread in all Central African
countries: Angola, Cameroon, Central African Republic, Chad, Congo,
Equatorial Guinea, Gabon, Sudan, Zaire, and Zambia. The risk is
a function of the frequency and degree of contact with contaminated
fresh water for bathing, wading, or swimming.
Prevention: The traveler cannot distinguish between infested and
non-infested water. Therefore, swimming in fresh water in rural
areas should be avoided. Bath water should either be heated to
50 degrees C (122 degrees F) for five minutes or treated with
chlorine or iodine as done for drinking water. If exposed, immediate
and vigorous towel drying or application of rubbing alcohol to
the exposed areas may reduce the risk of infection. Screening
procedures are available for those who suspect infection, and
schistosomiasis is treatable with drugs.
Recommendations: Avoid contact with potentially contaminated water.
Risk: For countries in Central Africa, there is a risk of rabies
infection particularly in rural areas, or in areas where large
numbers of dogs are found.
Prevention: Do not handle any animals! Any animal bite should
receive prompt attention. When wounds are thoroughly cleaned with
large amounts of soap and water, the risk of rabies infection
is reduced. Exposed individuals should receive prompt medical
attention and advice on post-exposure preventive treatment.
Recommendations: There are no requirements for vaccination, but
pre-exposure vaccination is recommended for:
- travelers visiting, for more than 30 days, foreign areas where
rabies is known to exist;
- veterinarians and animal handlers;
- spelunkers; and
- certain laboratory workers.
Pre-exposure vaccination does not nullify the need for post exposure
vaccine, but reduces the number of injections.
Summary of Recommendations for CENTRAL AFRICA
Travelers should (1) take Mefloquine (or equivalent) for malaria
prevention, (2) follow precautions to prevent insect bites, (3)
pay attention to the quality of their drinking water and food,
(4) have a dose of Immune Globulin (IG) or the Hepatitis A vaccine,
and (5) consider booster doses of tetanus (Td) and polio (eIPV)
vaccines. (6) Depending on the locations to be visited, planned
activities, and health of the traveler, the following vaccines
should be considered: Hepatitis B, Japanese Encephalitis, Typhoid,
Meningococcal, Rabies (pre-exposure), and Cholera. Details for
these recommendations are found in this document. (7) Finally,
the normal "childhood" vaccines should be up-to-date:
Measles, Mumps, Rubella (MMR Vaccine); Diphtheria,Tetanus, Pertussis
(DTP Vaccine) [ < 7 years of age]; and Polio vaccine.
Disease risks and precautions